Alpha GPC. GPC improves cognitive function significantly among people with mild to moderate mental impairment, including Alzheimer's disease and other dementias.Source:
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Alpha GPC (L-alphaglycerylphosphosphorylcholine), also known as choline alfoscerate is a phospholipid metabolite found concentrated in neuronal membranes. Made from lecithin, Alpha GPC is extremely well absorbed and crosses the blood brain barrier. In the brain Alpha GPC supports brain function and learning processes by directly increasing the synthesis and secretion of acetylcholine. Alpha GPC protects neurons and improves signal transmission by serving as a precursor to membrane phospholipids. Each Jarrow Formulas Alpha GPC 300 vegetarian capsule contains 300mg of elemental Alpha GPC.
It is well established that aging people suffer a deterioration of memory, acuity and other cognitive functions. Particularly frightening is an article published in The Lancet showing that memory complaint is an almost universal early symptom of dementia. Furthermore, says The Lancet article, mild cognitive impairment defines a transitional stage between normal aging and dementia.
The encouraging news is that researchers are discovering compounds that may be able to slow and even reverse the relentless deterioration that begins with mild memory impairment and often progresses to full-blown Alzheimer's disease or vaxcular dementia. One promising compound is glycerylphosphorylcholine (GPC).
What differentiates GPC from other compounds is that it not only increases brain acetylcholine levels, but it also enhances structural integrity of brain cells. The effects of GPC administration have been analyzed in ten human studies of neurological dysfunction involving 4,054 participants. The findings from a majority of these studies showed that GPC improves patient clinical conditions compared either to placebo or other cognitive enhancing drugs. In studies on people who had already suffered a stroke, GPC helped improve functional recovery. The latest findings from a multicenter clinical study concluded that GPC improves cognitive function significantly among people with mild to moderate mental impairment, including Alzheimer's disease and other dementias.The Need for Early Intervention
Physician-scientists now believe that mild cognitive impairment is a condition that precedes dementia. If this new theory were correct, it would mean that GPC represents a means of fighting the onset of early Alzheimer's disease, in addition to potentially boosting intellectual function in healthy aging people. Lucilla Parnetti MD, PhD, a published neuroscience researcher, believes that a firm case can be made for pre-emptive treatment with GPC. She notes that early acetylcholine depletion and cholinergic receptor demise begins approximately in the fourth of fifth decades of life, progressing thereafter. Dr Parnetti believes that GPC may be capable of preventing these normal signs of brain aging outright.GPC Softgels
In Europe, GPC is sold as a prescription drug to treat neurological dementia. It can be purchased as a dietary supplement in the United States. The minimum suggested dose for healthy people is 600 mg a day.Supplement Facts:Serving Size:
1 Vegetarian CapsuleAmount Per Tablet:
Alpha GPC (L-alphaglycerylphosphosphorylcholine) - 300mgOther Ingredients:
Cellulose, dicalcium phosphate and silicon dioxide. Suitable for vegetarians.Usage:
Take 1 to 2 capsules per day with a meal, or as directed by your qualified health consultant. Keep out of the reach of children.
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