APPLEWISE POLYPHENOL EXTRACT - Life Extension - 30 Vegetarian Caps (600mg)

APPLEWISE POLYPHENOL EXTRACT - Life Extension - 30 Vegetarian Caps (600mg)
Item# LEF01625
Retail Price: $21.00
Your Price: $15.75

The benefits of plant polyphenols are well known to health enthusiasts. These natural plant constituents block oxidative damage that lead to inflammation and accelerated biological aging of tissues.1

Recent studies by three separate laboratories have concluded that polyphenols extracted from apples extend life span in laboratory models by up to 12%2. Apples and especially their skin, are rich in an array of polyphenols. One particular major bioactive polyphenol, phloridzin, found in the skin of the apple, has been shown to act as a powerful agent against glycation and other destructive processes in the body. Phloridzin also regulates cell to cell signaling3 and supports healthy glucose levels in those already within normal range by inhibiting the glucose-6-phosphatase enzyme.4,5

Apple polyphenols can slow triglyceride absorption from the intestine by blocking pancreatic lipase, an enzyme specifically required to break down triglyceride fats.6,7 Additional research has shown that apple polyphenols can increase the protective antioxidant molecule paraoxonase by as much as 23%, thereby inhibiting dangerous lipid peroxidation and reducing an inflammatory cascade.8 Along with phloridzin, apples contain chlorogenic acid. Chlorogenic acid supports healthy glucose levels in those whose glucose levels are already within normal range by inhibiting the glucose-6-phosphatase enzyme,4,5 and by increasing some cellular mechanisms that are stimulated by insulin in liver cells.9

AppleWise Polyphenol Extract is extracted from the highest quality organically grown apples. Each 600 mg vegetable capsule contains 300 milligrams apple polyphenols.

Consumer note: Members taking supplements providing standardized pomegranate and coffee bean extracts, along with antiglycating nutrients like carnosine, benfotiamine and pyridoxal-5-phosphate may be deriving similar benefits as those provided by apple polyphenols.

Supplement Facts

Serving Size: 1 vegetarian capsule

Servings per Container: 30

Amount Per Serving

Amount - %DV

  • Apple (Malus sieversii) extract (whole fruit) [standardized to 50% polyphenols (300 mg), from organically grown apples] - 600mg

Other Ingredients: vegetable cellulose (capsule), rice flour, vegetable stearate.

Suggested Use: Take one capsule one to four times daily with or without food, or as recommended by a healthcare practitioner.

If you have any questions, please contact us at or 1-888-771-3905.

The statements made here have not been evaluated by the FDA. The foregoing statements are based upon sound and reliable studies, and are meant for informational purposes. Consult with your medical practitioner to determine the underlying cause of your symptoms. Please always check your purchase for possible allergins and correct dosage on the bottle before use.

While we work to ensure that product information is correct, on occasion manufacturers may alter their ingredient lists. Actual product packaging and materials may contain more and/or different information than that shown on our Web site. We recommend that you do not solely rely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. For additional information about a product, please contact the manufacturer. Content on this site is for reference purposes and is not intended to substitute for advice given by a physician, pharmacist, or other licensed health-care professional. You should not use this information as self-diagnosis or for treating a health problem or disease. Contact your health-care provider immediately if you suspect that you have a medical problem. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease or health condition. Life Extension Institute assumes no liability for inaccuracies or misstatements about products.