ArthroPro is comparable to natural pain relief formula with added protective nettle aspirin and ginger. Source: Life Extension Foundation Ingredients: See below. Sale Price: $39.99 Take advantage of FREE air shipping in the USA! Read More . . . Finally, a product comparable to natural pain relief formula with added protective nettle aspirin and ginger! Multiple degenerative processes occur due to agents that promote systemic inflammation. These inflammatory agents include, cyclooxygenase-2 (COX-2), 5-lipooxygenase (5-LOX), and damaging cytokines known as tumor necrosis factor alpha (TNF-a) and interleukin-1 beta (IL-1b). Other harmful enzymes are collagenase and phospholipase. Thus, the goal is to block all the destructive pathways involved. The ArthroPro multi-nutrient formula: Suppresses TNF-a and IL-1b through its super concentrated nettle leaf extract ingredient Inhibits 5-LOX with the inclusion of inflammatory blocker 5-Loxin Protects against the damaging effects of the COX-2 enzyme with the agent Nexrutine Includes gingerols (from ginger powder extract), which restrain the cyclooxygenase and lipoxygenase cascade and the production of thromboxane and leukotriene, powerful triggers of pain and inflammation Helps to maintain healthy joint cartilage with the addition of glucosamine and chondroitin sulfate, which also controls collagenase and phospholipase Supplemental Facts Serving Size: 2 capsules Servings Per Container: 60 Amount Per Serving: Nettle (Urtica dioica), powdered extract (leaf) - 562.5mg Chondroitin sulfate - 400mg Nexrutine (Phellodendron amurense) (bark extract) - 375mg N-acetyl d-glucosamine (derived from shellfish) - 250mg Glucosamine sulfate (derived from shellfish) - 250mg 5-Loxin [standardized for 3-O-acetyl-11-keto-b-boswellic acid (AKBA) minimum 30% on dried basis (11.25 mg)] - 37.5mg Ginger, powdered extract (rhizome) 5% gingerols - 30mg Other ingredients: gelatin and water Dosage and Use: Take two capsules in the morning and two capsules in the evening with food, or as directed by a healthcare professional. Caution: If you are allergic to shellfish, do not use this product. Consult your healthcare professional. If you have impaired kidney or liver function, use only under physician supervision. How to Order To order online, click on the "Order" box below. To see a list of all supplements, please check our Index or use our Search feature. If you have any questions, please contact us at info@lifeextensionvitamins.com or 1-888-771-3905. arthroproRetail Price: $49.95Sale Price: $39.99 120: caps FREE AIR MAIL SHIPPING IN THE UNITED STATES! The statements made here have not been evaluated by the FDA. The foregoing statements are based upon sound and reliable studies, and are meant for informational purposes. Consult with your medical practitioner to determine the underlying cause of your symptoms. Copyright 1997-2009 Life Extension Vitamin Supplies and Life Extension Institute, Inc. All rights reserved.