Summary When considering breast cancer treatment options, physicians and patients alike must sort through an overwhelming bombardment of information. This protocol attempts to simplify complicated scientific research and bring to the forefront the most up-to-date, polytherapeutic approach to cancer treatment available. It utilizes multimodality therapies, including integrating surgery, anticancer drugs, irradiation, hormone therapy, supplementation, and diet modification in a comprehensive approach to fight breast cancer. As discussed in this protocol, cancer growth is based on many complicated interactions via numerous physiological pathways within the body. And despite the huge strides in scientific research, there are still many unanswered questions regarding cancer's growth and development. What we do know is that there is overwhelming research supporting an integrated approach to the treatment of cancer and the information put forth within this article reflects that research. Additionally, research supports using supplementation to improve the efficacy of chemotherapy drugs and radiotherapy. In fact, combining certain individual supplements can create a synergism that can effectively block or impede certain cancer pathways. Therefore, the following supplementation regimen is suggested. Please read the entire protocol before considering this regimen because there are certain cautions to consider. As always, consult your physician before beginning any regimen. 1. Indole-3-carbinol, a 200-mg capsule twice daily, if you weigh under 120 lbs or three 200-mg capsules daily in two divided doses if you weigh over 120 lbs. Take two 200-mg capsules twice daily, if you weigh over 180 lbs. Caution: Pregnant women should not take indole-3-carbinol because of its modulation of estrogen. 2. Curcumin, 900 mg, 4 capsules 3 times daily on an empty stomach. Note the caution earlier in this protocol. 3. Lightly caffeinated green tea extract, 350 mg, 5 capsules 3 times daily with meals. Use decaffeinated green tea extract if you are sensitive to caffeine or want to use the less-stimulating version with the evening dosage. 4. CLA or CLA with Guarana, 3000-4000 mg daily of CLA and about 300 mg of guarana, early in the day. 5. Melatonin, 3-50 mg at bedtime. 6. Phyto Food Powder (broccoli, cabbage, and other cruciferous vegetables that provide sulphoraphane and other cancer-fighting plant extracts), 1-2 tbsp daily. 7. Se-methylselenocysteine, 200-400 mcg daily. 8. CoQ10, 100 mg 3 times daily. Note the caution stated in this protocol. 9. Mega EPA (with DHA), 8 capsules daily, supplying 3200 mg of EPA and 2400 mg of DHA. Take with nonfiber meals. 10. Vitamin D3, 4000-6000 IU taken daily on an empty stomach with monthly blood testing to monitor for toxicity. Reduce dosage at 6 months. 11. Water-soluble vitamin A, 100,000-300,000 IU daily with monthly blood testing to monitor for toxicity. Reduce dosage at 6 months. 12. Vitamin E succinate (tocopheryl succinate), 1200 IU daily. 13. Gamma E Tocopherol/Tocotrienol, 1 capsule daily. Take an additional 200 mg of palm-oil tocotrineols as an adjuvant therapy. 14. Vitamin C, 4000-12,000 mg throughout the day. 15. Gamma linolenic acid, 1200 mg a day (4 capsules of a borage oil supplement called Mega GLA will supply this amount). 16. Whey protein concentrate-isolate, 30-60 grams daily. 17. Bone Assure provides calcium, magnesium, and bone-protecting nutrients. Take 6 capsules at bedtime. 18. Vitamin K, 10 mg daily. 19. Silicon, 6 mg daily. (Jarrow's Biosil is recommended.) 20. Life Extension Mix (multinutrient formula), 3 tablets 3 times daily. Reminder: Bisphosphonate drug therapy is strongly encouraged for all breast cancer patients as well as Arimidex drug therapy if appropriate. For more information Contact the American Cancer Society, (800) ACS-2345. Sources for National Cancer Institute Information
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