Source: Allergy Research Group Ingredients: See below Sale Price: $18.99 + Free Shipping Take advantage of FREE air shipping in the USA!
Read More . . . Overview The health and integrity of the epithelial lining of the gastrointestinal tract is important for proper absorption of nutrients, healthy microbial balance in the gut, and homeostasis throughout the body. When the gastrointestinal tract has increased intestinal permeability (also known as “leaky gut”), an environment results that is conducive to inadequate absorption of nutrients, and increased absorption of toxins, pathogenic bacteria and inflammatory substances, which can potentially weaken immunity and health. Increased intestinal permeability can occur among individuals with chronic stress or allergies, or who consume caffeine, alcohol, or foods processed with chemical additives, or who overuse prescription and over the counter drugs, or who are exposed to environmental contaminants such as car exhaust, perfumes and cleaning chemicals. Dietary supplementation with nutrients the body uses to produce healthy epithelial tissue, regulate transit time and balance microbiology may support gastrointestinal health.* Digestive support may also benefit individuals with increased intestinal permeability.* Description ButyrEn is an enteric-coated, extended shelf-life formulation of the calcium and magnesium salts of butyric acid, designed specifically for delayed release in the gastrointestinal tract. Butyric acid is a short-chain fatty acid (SCFA) produced by certain probiotic bacteria, and appears to support mucosal integrity.* Butyric acid may support the integrity of the colonic mucosa by acting as a primary fuel for the colonic epithelium (colonocytes).* Butyric acid (“butyrate” when in salt form) is an important SCFA for this reason.* Colon health is directly related to the metabolic processes occurring in the gut, which itself is directly related to diet. In this way, it can be said that the food we eat, which will in part determine the health of the colon, is a way to communicate with our environment. But how does our food communicate with our environment? It does so because when we take food into our mouths, it begins a process of transformation as it moves through the stomach, then the intestines, and the waste part goes out again into the environment. During this trip, the food becomes changed in structure, or digested. The digested nutrients are free to be absorbed by the circulatory system and delivered to the necessary sites. Upon delivery of the nutrients, the cells receive a message and then the cells create a reaction, the type of reaction depending on the nutrient involved. Butyrate is created when colonocytes act metabolically on undigested fiber in the colon. This fiber can be considered a prebiotic agent. Prebiotics escape enzymatic digestion in the upper gastrointestinal tract and enter the large intestines unchanged. Instead of being excreted in the stool, these substances are fermented by colonic flora to yield SCFAs such as butyrate. The SCFAs, in turn, will stimulate the bifidobacterium in the large intestine, which may yield health benefits such as boosting the intestinal immune response, producing vitamins and enzymes, producing organic acids that support normal intestinal pH, and supporting the structure and functional integrity of the epithelial lining in numerous ways. Butyrate is absorbed by the colonocytes in the proximal colon via passive diffusion and by active transport mechanisms. The mucosal metabolic fluxes of both butyrate and glutamine (a conditionally essential amino acid) have been shown to be connected to several aspects of intestinal health, including healthy intestinal immune response.* The ability of colonocytes to utilize butyrate can contribute to a healthy condition of the colon or bowel.* Suggested use: As a dietary supplement, 1 or 2 tablets three times daily with meals, or as directed by a healthcare practitioner. Serving Size: 1 tablet Servings per container: 100 Amount per serving:
These nutrients are of the highest quality and purity obtainable, free of all common allergens (antigens), and do not contain preservatives, diluents, or artificial additives. Keep in a cool, dry place, tightly capped. *This statement has not been evaluated by the U.S. Food and Drug Administration. The product is not intended to diagnose, treat, cure, or prevent any disease. References Velazquez OC, Lederer HM, Rombeau JL. Butyrate and the colonocyte. Production, absorption, metabolism, and therapeutic implications. Harrison Department of Surgical Research, University of Pennsylvania Medical Center, Philadelphia, 19104, USA. Stokrova J, Sovova V, Sloncova E, Korb. J Int J Mol Med 1999 Dec:4(6):669-74. Burke A, Lichtenstein GR, Rombeau JL. Baillieres Clin Gastroenterol 1997 Mar;11(1):153-74. Duffy MM, Regan MC, Ravichandran P, O’Keane C, Harrington MG, Fitzpatrick JM, O’Connell PR. Dis Colon Rectum 1998 Nov;41(11):1399-405. Grizard D, Barthomeuf C. Non-digestible oligosaccharides used as prebiotic agents: mode of production and beneficial effects on animal and human health. Reprod Nutr Dev 1999 Sep-Dec;39(5- 6):563-88. Santini V, Gozzini A, Scappini B, Caporale R, Zoccolante A, Rigacci L, Gelardi E, Grossi A, Alterini R, Ferrini PR. Haematologica 1999 Oct:84(10):897-904. Krishnan S, Rajan DP, Ramakrishna BS. Scand J Gastroenterol 1998 Mar;33(3):242-6. |
FREE AIR MAIL SHIPPING IN THE U.S.!  The statements made here have not been evaluated by the FDA. The foregoing statements are based upon sound and reliable studies, and are meant for informational purposes. Consult with your medical practitioner to determine the underlying cause of your symptoms. Copyright 1997-2008 Life Extension Vitamin Supplies and Life Extension Institute, Inc. All rights reserved. |