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7-Keto DHEA has been shown to safely increase thermogenesis, improving fat loss benefits of diet and exercise three-fold. Antioxidants are added based on the effect 7-Keto has in boosting mitochondrial oxidation.
Source: Life Extension Foundation
Ingredients: See below.
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In 1981, the Life Extension Foundation introduced DHEA (dehydroepiandrosterone) to its members through an article that described the multiple benefits that this hormone might produce. However, the general public did not learn about DHEA until 1996, when the benefits of DHEA were touted by the news media and in several popular books. DHEA became credible to the medical establishment when the New York Academy of Sciences published a book entitled DHEA and Aging. This book provided scientific validation for the many life extending effects of DHEA.
It has been shown that the hormone DHEA often declines 40.8-72.8% by age 70 or later, leading to hormonal imbalances that can affect one's quality of life. Peak blood levels of DHEA occur at approximately age 25, decreasing progressively thereafter. Thus, scientists have been looking at ways of restoring DHEA to youthful levels, and are now discovering mechanisms by which this hormone protects against age-related decline.
Since 1981, several hundred studies have been published on DHEA's possible benefits. One study investigated immune functions and DHEA using rats as test subjects. The scientists showed that DHEA administration to rats supports specific immune function known to be lacking in the elderly.
Another study focused on the various benefits of DHEA supplementation, and noted that DHEA's protective effect could be of benefit to the normal aging brain. Some studies have reported DHEA may improve mood and alleviate melancholy. In fact, as highlighted in two studies, participants have reported that they feel better when taking DHEA.
In still another investigative study doctors noted that DHEA is one factor that determines lumbar spine density in aging men. In women, it has been shown that DHEA helps to protect bone mineral density. DHEA's role in supporting a healthy circulatory system and joint/bone health was also highlighted in the Journal of the Medical Association of Thailand.
DHEA Precautions for Men
Before attempting to restore DHEA to youthful levels, men should know their serum PSA (prostate specific antigen) level and have passed a digital rectal exam. Men with prostate cancer or severe benign prostate disease are advised to avoid DHEA since it can be converted into testosterone (and estrogen). Therefore, men are advised to have a PSA and digital rectal exam before initiating DHEA to rule out existing prostate disease.
When taking DHEA we also recommend taking the following other nutrients:
- Vitamin E - 400 IU daily
- Selenium - 200 mcg daily
- Super Absorbable Soy Isoflavones - 55.5 mg daily
- Gamma E Tocopherol with Sesame Lignans - 200 mg daily
- Lycopene Extract - 20-40 mg daily
- Saw Palmetto Extract - 160 mg twice daily
- Pygeum Extract - 50 mg twice daily
- Nettle Extract - 120 mg twice daily
- Boron - 3-10 mg daily
It is important for men over 40 to consult their physician to check their PSA and DHEA-S serum levels every six to twelve months thereafter. Men should also periodically check their blood levels for free testosterone and estrogen to make sure that DHEA is following a youthful metabolic pathway. See the Male Hormone Modulation protocol for additional hormone balance testing that can be done at the same time serum DHEA and PSA levels are being tested.
DHEA Precautions for Women
When taking DHEA we also recommend taking the following other nutrients to maintain a healthy balance:
- Melatonin - 300 mcg to 3 mg nightly
- Vitamin E - 400-800 IU daily
- Indole-3-carbinol - 200 mg daily
- Vitamin D3 - 1000-1400 IU daily
- Gamma Tocopherol with Sesame Lignans - 200 mg daily
- Super Absorbable Soy Isoflavones - 55.5 mg daily
Women should consider estrogen and testosterone testing when they take their DHEA blood test in order to evaluate DHEA's effect on their blood levels of these hormones.
Women who have been diagnosed with an estrogen-dependent cancer should consult their physicians before beginning the DHEA restoration process. Women taking DHEA should refer to the Female Hormone Modulation protocol for information about restoring youthful hormone balance.
7-Keto DHEA, a natural metabolite of DHEA, has been shown to safely increase thermogenesis, improving fat loss benefits of diet and exercise three-fold. Antioxidants are added based on the effect 7-Keto has in boosting mitochondrial oxidation.
Supplement Facts
Serving Size: 1 capsule
Servings Per Container: 60
Amount Per Serving
- Vitamin C (as ascorbyl palmitate) - 11 mg
- Vitamin E (as D-alpha tocopheryl succinate) - 25 IU
- 7-Keto DHEA (3 -Acetyl-7-oxo-dehydroepiandrosterone) - 100 mg
- Ascorbyl palmitate - 25 mg
- Curcumin C3 Complex� Turmeric (root) extract (Curcuma longa) [Standardized for 95% total curcuminoids (23.75 mg)] - 25 mg
- DHEA (dehydroepiandrosterone) (pure free base pharmaceutical grade) - 25 mg
- Green tea extract, decaffeinated (Camellia sinensis) leaf [Standardized for minimum 90% polyphenols (22.5 mg)] - 25 mg
- Whole grape extract (Vitis vinifera) and Polygonum cuspidatum (root) extract [Standardized to 35% Resveratrol (1 mg)] - 3 mg
Other ingredients: rice flour, gelatin, magnesium stearate.
7-keto U.S. Patents No. 5,292,730; 5,296,481; 5,585,371; 5,641,766; 5,869,709; 5,885,977.
Curcumin C3 Complex� and Nature's Bioprotectant are registered trademarks of Sabinsa Corp.
Dosage and Use
Take one capsule upon waking and one capsule before midday meal, preferably on an empty stomach.
Caution: Those with hormone related cancers such as prostate cancer or breast cancer should not use DHEA. DHEA serum blood tests are suggested 3 to 6 weeks after initiating DHEA supplementation to optimize individual needs.
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The statements made here have not been evaluated by the FDA. The foregoing statements are based upon sound and reliable studies, and are meant for informational purposes. Consult with your medical practitioner to determine the underlying cause of your symptoms.
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