Source: Life Extension Foundation Ingredients: See below. Sale Price: $29.99 Quantity Price: 4 bottles - $116 Take advantage of FREE air shipping in the USA!
Read More . . . THE IMITATORS DO NOT OFFER THIS FORMULA. IMITATORS DO NOT OFFER TOCOTRIENOLS AND THE CORRECT PROPORTION OF GAMMAS!! The term "vitamin E" refers to a family of eight related, lipid-soluble, antioxidant compounds widely distributed in plants. The tocopherol and tocotrienol subfamilies are each composed of alpha, beta, gamma and delta vitamers having unique biological effects. Different ratios of these compounds are found in anatomically different parts of a plant. For example, the green parts of a plant contain mostly alpha tocopherol and the seed germ and bran contain mostly tocotrienols. When this family of compounds was first discovered and determined to be essential for health, a standardized test for its activity was devised for which the members of the family were rated for their biological activity. In one test, alpha tocopherol scored highest and was rated 100% with all others having lower ratings. In accordance with this rating, alpha tocopherol was deemed to be the essential compound and was called vitamin E. One International Unit (IU) of vitamin E activity is the activity under this rating of 1 mg of the plant-derived form of alpha tocopherol. Since the original rating method was established, many additional important biological effects of these compounds have been discovered and many nutritional scientists now consider that rating method to be incomplete. For example, by the original rating, gamma tocopherol was only 10 to 30% as strong as alpha tocopherol, yet recent studies have shown it to be essential for maintaining the health of cell membranes, especially if alpha tocopherol is being supplemented. New studies continue to elucidate the unique benefits of individual members of the vitamin E family. For example, tocotrienols have been shown to lower cholesterol, prevent LDL oxidation, and reduce atherosclerotic plaque formation more effectively than tocopherols. For these and other reasons, the original definition of vitamin E has been enhanced to include all eight family members and the related compounds that convert to them in the body. Vitamin E compounds are usually produced and made available in esterified form as alpha tocopheryl acetate or alpha tocopheryl succinate. Neither of these forms has any antioxidant activity until converted to alpha tocopherol in the body, but they are much more stable with respect to storage time and temperature than the unesterified forms. Moreover, while the acetate form is rapidly activated within the body, activation of the succinate form is slower. The succinate form appears to access and benefit areas of the tissues that are unavailable to the other forms. For this reason, there is a tendency to regard alpha tocopherol succinate (VES) as a distinctly different and beneficial compound. VES appears to have longer half-life in the body, less effect on blood clotting, and does not interfere with vitamin A and K absorption. It is also more beneficial for cancer therapy according to several published studies. Serious vitamin takers prefer cold-water dispersible dry powder vitamin E supplements in the form of alpha tocopheryl succinate or acetate because the cold-water dispersible forms are efficiently absorbed even when taken on an empty stomach or with a low-fat meal. The non-cold water dispersible (oil) forms of vitamin E may be poorly absorbed unless taken with several grams of fats or oils. Cold-water dispersible vitamin E is twice as expensive as soybean oil E-acetate, but the cold-water dispersible forms are more efficiently absorbed. Both acetate and succinate vitamin E can come from natural sources. The importance to the consumer is how well the vitamin E absorbs into the bloodstream. Cold-water dispersible vitamin E, whether in a succinate or acetate form, always comes in a white dry powder, while non cold-water dispersible natural and synthetic acetate forms of vitamin E are always in a thick brown oil. While 100 IU or more of supplemental vitamin E a day has been shown to reduce the risk of heart attacks in healthy people, those with pre-existing coronary artery disease often take 800 to 1600 IU a day based on the pioneering work of the Shute brothers in the mid 1940s. One or more members of the vitamin E family may also:
If you are taking anti-clotting medication, consult with your doctor before taking this product. Ingestion of total vitamin E products in excess of 1200 IU daily may interfere with absorption and metabolism of vitamins A and K. If you take vitamin E, you're probably not getting its full benefits! All vitamin E supplements contain alpha tocopherol, but few contain gamma tocopherol. It doesn't matter whether you take natural or synthetic vitamin E, the form used is almost always alpha. There's nothing wrong with alpha tocopherol, but anything taken unbalanced with other related vitamins may not be best. If you expect to obtain optimal antioxidant protection, you should take gamma tocopherol as well. A study in Proceedings of the National Academy of Sciences (April 1997) suggests that it could be dangerous to take high doses of alpha tocopherol without also consuming gamma tocopherol. What made this study interesting was that it showed that high doses of alpha tocopherol displace gamma tocopherol in tissues. While alpha tocopherol inhibits the production of free radicals to some degree, it is gamma tocopherol that is required to trap and neutralize existing free radicals. A recent study showed that gamma tocopherol protected brain cells against free radical damage. This study was critical of people taking vitamin E supplements that do not contain at least a 20% gamma tocopherol fraction. Gamma tocopherol has also been shown to inhibit growth of melanoma cells in mice by as much as 50%. One dangerous compound that gamma tocopherol neutralizes is peroxynitrite. Peroxynitrite is harmful to cells because of its powerful oxidizing and nitrating properties. The scientists who wrote the National Academy of Sciences report insist that vitamin E supplements do not contain any gamma tocopherol. The Life Extension Foundation's Gamma E Tocopherol contains the highest percentage of gamma tocopherol found on the supplement market in an encapsulated liquid vitamin E formula. It can be used to augment regular alpha tocopherol supplements or as a one-a-day vitamin E supplement on its own. Dosage and Use One softgel daily is suggested for healthy people. The Life Extension Foundation was the first to introduce gamma tocopherol, and has since enhanced the formula with potent doses of palm oil-derived tocotrienols, the highest quality available. Serving size: 1 softgel capsule Amount per serving -- %Daily Value Vitamin E 98.8 iu 329% Mixed Tocopherols Typical distribution:
Typical distribution:
Other ingredients: gelatin, glycerin, water and rosemary extract. How to Order To order online, click on the "Order" box below. To see a list of all supplements, please check our Index or use our Search feature. If you have any questions, please contact us at info@lifeextensionvitamins.com, 1-510-527-3005 or 1-888-771-3905. |
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| Gamma E Quantity Price for 4 | | | ~ Gamma Tocopherol Under Attack - Not the Whole Story |
FREE AIR MAIL SHIPPING IN THE UNITED STATES!  The statements made here have not been evaluated by the FDA. The foregoing statements are based upon sound and reliable studies, and are meant for informational purposes. Consult with your medical practitioner to determine the underlying cause of your symptoms. Copyright 1997-2008 Life Extension Vitamin Supplies and Life Extension Institute, Inc. All rights reserved. |