Source: Life Extension Foundation
Ingredients: See below.
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For Rheumatoid Arthritis Scientists at the University of Pennsylvania have reported that high doses of gamma-linolenic acid (GLA) were highly effective in treating rheumatoid arthritis. An earlier study by the same group had shown that administration of 1,100 mg of GLA per day from borage seed oil reduced synovitis in six of seven patients with rheumatoid arthritis. GLA is rapidly converted to dihomogamma-linolenic acid, the immediate precursor of prostaglandin E1 which is a potent anti- inflammatory agent.
Diabetes and GLAThe majority of diabetics will eventually develop some degree of neuropathy. Conventional medicine offers little in the prevention or treatment of diabetic neuropathy, yet there is a great deal of published information showing that the proper use of dietary supplements can be of significant benefit.
Diabetes is associated with a fatty acid imbalance. In experimental models, essential fatty acid desaturation contributes to reductions in peripheral nerve conduction velocity and blood flow. This fatty acid imbalance may be corrected by dietary supplements that contain gamma-linolenic acid (GLA), such as borage oil. In animal studies, significant improvements in blood flow and nerve-conduction velocity were observed in response to GLA supplementation.
Nerve conduction and perfusion deficits in diabetic rats have been corrected by a combination of antioxidant and gamma-linolenic acid (GLA) supplements. A deficit in sciatic nutritive endoneural blood flow was corrected by 34.8% with GLA therapy, and by 24.8% with free radical scavenger therapy. When both treatments were combined, a flow improvement of 72.5% was observed. This study showed a synergistic effect of antioxidant and omega-6 essential fatty acid (GLA) when used in combination against diabetic neuropathy.
Deficient and toxic neuropathies can be alleviated by improving lifestyle and dietary factors. The following combinations of nutritional supplements might be particularly effective:
Gamma-linolenic acid (GLA), fish oil concentrate, and ascorbyl palmitate offer a potential synergistic approach to correcting a fatty acid imbalance by enhancing blood flow to the nerves, and protecting against free radicals. A suggested regimen would be to take 3 capsules of Mega GLA (gamma-linolenic acid supplement), along with 3 capsules of Mega EPA (fish oil concentrate), and 500 mg of ascorbyl palmitate twice a day. If symptoms alleviate or disappear, the dose of GLA and EPA could be reduced to 2 capsules twice a day.
Other benefits of GLA include:
- Vasodilation of blood vessels which can reduce high blood pressure.
- Reduction of abnormal blood clotting which can reduce the risk of heart attack and stroke.
- Enhanced regulation of immune response, specifically a reduction in autoimmune dysfunction, the underlying cause of rheumatoid arthritis.
- Enhanced defense against abnormal cell proliferation which may prevent and even reverse some cancers.
- Elimination of common skin disorder such as eczema.
- Slowing of some aspects of normal aging through a mechanism similar to that of calorie restriction.
Rheumatoid arthritis patients should take five capsules of MEGA GLA per day. Osteoarthritis patients may also benefit from the anti-inflammatory properties of GLA.
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