Migra-Eeze - Standardized Butterbur-Ginger-Riboflavin Formula MygraFew - Standardized Feverfew Extract Magnesium 500 - High-Yield of Elemental Magnesium Complete Vitamin B Complex - Balanced Formula Three Month Supply - $71.99 with Free Shipping In the brain, fluctuating magnesium levels can send blood vessels into spasm, stretching delicate nerve endings and generating pain in the process. In addition to pain, migraine sufferers also may experience nausea and vomiting, visuals changes, and sensitivity to light and sound. Magnesium supplements are generally well tolerated by healthy individuals, with the most common side effect being diarrhea. For people with kidney disease, however, magnesium can be unsafe, and should not be taken without a doctor's supervision. In addition to magnesium, vitamin B and an herb known as feverfew have been shown to be effective in the prevention and treatment of migraines. Vitamin B-2, or riboflavin, works by increasing the energy production of structures called mitochondria, which serve as microscopic power plants for cells in the body and brain. Research has demonstrated that mitochondria in the brains of migraine sufferers produce significantly less energy than mitochondria in the brains of people without the condition. Feverfew, also known as bachelor's button, has been used in the treatment of headaches for hundreds of years. Feverfew helps maintain normal blood vessel bone by reducing platelet aggregation, serotonin release from platelets and blocking the formation of pro-inflammatory mediators. Butterbur's principal active constituent, petasin, reduces smooth muscle spasms and helps relax the constriction of cerebral blood vessels. Butterbur's ability to relax constricted arteries and smooth muscle may help control head cavity discomfort. Life Extension's new Migra-Eeze contains butterbur root extract standardized to provide 22.5 mg of petasins with each daily dose of two softgels. Riboflavin (vitamin B2) and ginger are included based on the ability of these nutrients to exert functional changes that may also guard against head cavity discomforts.   migrainpak1$71.99 1: pak/4_bottles.ea FREE AIR MAIL SHIPPING IN THE UNITED STATES! The statements made here have not been evaluated by the FDA. The foregoing statements are based upon sound and reliable studies, and are meant for informational purposes. Consult with your medical practitioner to determine the underlying cause of your symptoms. Copyright 1997-2010 Life Extension Vitamin Supplies and Life Extension Institute, Inc. All rights reserved.