Life Extension Foundation
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The anatomy of the female urinary tract differs greatly from men, resulting in the need for additional nutritional support for women. A wealth of published studies indicates that cranberry polyphenols may help to support a healthy urinary tract.
Of particular importance is the flavonoid content of the cranberry, including anthocyanins and proanthocyanidins. These natural compounds exert powerful antioxidant effects that can reduce oxidative stress. Recent clinical data suggest that the proanthocyanidins found only in cranberries also possess unique molecular features that specifically promote urinary system health.
In a significant advance, Life Extension® has identified a unique compound available overseas but little-known in the United States that provides a synergistic complement to the whole cranberry's phytonutrient profile. UTIRose™ is derived from Hibiscus sabdariffa, a species native to Europe, Asia, and Africa. Scientific analysis has shown that this species' flower and calyx (the green floral envelope surrounding the blossom) are rich in active polyphenols, including flavonoids, sambubiosides, and proanthocyanidins. Of special importance is a flavonoid found in Hibiscus sabdariffa called gossypetin (3,5,7,8,3,'4'-hexahydroxy flavone), which has been shown to provide support for urinary system health.
UTIRose™ is derived from Hibiscus sabdariffa, a species native to Europe, Asia, and Africa. Scientific analysis has shown that this species’ flower and calyx (the green floral envelope surrounding the blossom) are rich in active polyphenols, including flavonoids, sambubiosides, and proanthocyanidins.
Of special importance is a flavonoid found in Hibiscus sabdariffa called gossypetin (3,5,7,8,3,’ 4’-hexahydroxy flavone), which has been shown to provide support for urinary system health. Life Extension uses a unique, patented process in the manufacture of Optimized Cran-Max® with UTIRose™. Each capsule supplies the complete phenolic profile of the whole cranberry plus hibiscus polyphenols in a standardized, highly absorbable, concentrated form.
The suggested dose of one capsule twice daily delivers 500 mg of Cran-Max®, to provide the anthocyanin equivalent of seven 8 oz. glasses of Ocean Spray® Cranberry Juice Cocktail.Supplement FactsServing Size:
1 vegetarian capsuleServings Per Container:
60Amount Per Serving
- UTIRose™ (Hibiscus sabdariffa) extract (flower, calyx) [standardized to 50% total phenolics (50 mg), providing sambubiosides] - 100mg
- Cranberry infused whole fruit - 250mg
vegetable cellulose (capsule), microcrystalline cellulose, vegetable stearate, silicon dioxide.
This product contains NO milk, egg, fish, peanuts, crustacean shellfish (lobster, crab, shrimp), soybeans, tree nuts, wheat, yeast, gluten, corn, or rice. Contains NO sugar, and no artificial sweeteners, flavors, colors, or preservatives.
Cran-Max® registered trademark of BDM Technologies, LLC.
UTIrose™ is a trademark of Burgundy Botanical Extract.
Bio-Shield® is a registered trademark of Bio-Nutra Technologies, LLC.Dosage and Use:
Take one capsule twice daily with or without food, or as recommended by a healthcare practitioner.Caution:
Avoid use during pregnancyReferences
- Cochrane Database Syst Rev. 2004;(2):CD001321
- Mol Nutr Food Res. 2007 Jun;51(6):732-7.
- Evid Based Med. 2008 Aug;13(4):105.
- BMJ. 2001;322:1-5.
- Phytomedicine. 2007;14(4):237-41.
- J Med Food. 2009 Apr;12(2):259-70.
- Crit Rev Food Sci Nutr. 2002;42(3 Suppl):273-8.
- Wien Med Wochenschr. 2007;157(13-14):325-30.
- The Antiseptic. 2002 Mar; 99(3): 81-2.
- Cran-Max® versus Ocean Spray Cranberry Juice cocktail bioactive comparison. Independent laboratory analysis. Tucson, AZ: Atlas Bioscience, Inc.; 2006.
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