Optimized Resveratrol - Life Extension - Non-GMO - 60 Vegetarian Capsules

Optimized Resveratrol - Life Extension - Non-GMO - 60 Vegetarian Capsules
Item# LEF-02030
Retail Price: $46.00
Your Price: $34.50

Optimized Resveratrol - Non-GMO, 60 vegetarian capsules, Item# 02030 (formerly Item# 01430)

Quantity Price for 4

Life Extension has identified certain compounds that mimic calorie restriction’s ability to trigger youthful gene expression, the process by which genes transmit signals that slow certain aspects of aging. These compounds include trans-resveratrol (which researchers contend is the most active constituent), whole grape extract, quercetin, plus certain compounds found in berries, including trans-pterostilbene and now fisetin.

Findings from published scientific literature indicate that resveratrol may be the most effective compound for maintaining optimal health and promoting longevity.144 Resveratrol is a phytoalexin, a polyphenolic compound which is produced by Vitis vinifera as a response to attack by molds. Because of the widespread use of pesticides in modern wine making, including the practice of copper sulfation, the level of resveratrol in modern wines has plummeted. Red wine contains resveratrol, but the quantity varies depending on where the grapes are grown, the time of harvest and other factors. In fact, usually only one to three mg of resveratrol per liter of red wine is currently found, even in the most robust red wines. After years of relentless research, a standardized resveratrol extract is now available as a dietary supplement.

Research funded by the Life Extension Foundation showed that a combination of low-dose (20 mg) resveratrol plus grapeseed extract mimicked many of the favorable gene expression changes seen in calorie-restricted animals. Other studies, however, indicate that higher doses may be needed to obtain all of resveratrol’s positive benefits including promoting healthy insulin sensitivity, enhanced mitochondrial function, reduced expression of inflammatory factors, and protection against the effects of a high-fat diet.145-159

Life Extension has evaluated published studies on resveratrol to establish the doses humans might need to take to duplicate the remarkable laboratory findings. The results of Life Extension’s analysis yield a wide range of potentially effective doses: from 20 to 250 mg a day and higher. The resveratrol potency you choose may be based on your current state of health and/or your desire to reach the upper limits of a healthy human life span.

Pterostilbene, a stilbene compound from the same family as resveratrol, has been shown to work synergistically with resveratrol, to unlock one’s longevity genes … thus conferring even greater anti-aging benefits. In laboratory tests, pterostilbene has shown promise for supporting cardiovascular health, glucose levels that are already within normal range, anti-aging and cognitive function.178-185 It helps improve mitochondrial function and supports healthy metabolic function by activating SIRT1 and mimicking calorie restriction.186,187 It has also shown potential to ease inflammation and support antioxidant activity.181,185

Fisetin, found in strawberries, has the power to “switch on” cell signaling molecules that support youthful gene expression, DNA protection, and healthy cellular function.160 Fisetin also supports aging neurons in the presence of oxidative stress.161-165 And, most importantly, it works in synergy with resveratrol. Researchers have uncovered compelling evidence of fisetin’s ability to stabilize resveratrol by shielding it from metabolic breakdown,166 thus extending its beneficial effects! So naturally we added it, along with these other four calorie restriction mimics, to this most advanced resveratrol formulation.

Ratings based on results of the 2016 ConsumerLab.com Survey of Supplement Users. More information at www.consumerlab.com/survey2016.

Supplement Facts

Serving Size: 1 vegetarian capsule

Amount Per Serving

  • Trans-Resveratrol [from Japanese knotweed (root)] - 250mg

  • Quercetin (as quercetin dihydrate) - 150 mg

  • Red grape (fruit) and wild blueberry (fruit) blend [providing polyphenols, anthocyanins, OPCs] - 85mg

  • Trans-Pterostilbene (from pTeroPure®) - 0.5mg

  • Fisetin [from (Rhus succedanea) extract (stem)] - 10mg


Other ingredients: vegetable cellulose (capsule), microcrystalline cellulose, vegetable stearate, silica, maltodextrin.

Non-GMO

pTeroPure® is a registered trademark of ChromaDex, Inc.

Dosage and Use: Take one capsule daily with or without food, or as recommended by a healthcare practitioner.

Caution: If you are taking anti-coagulant or anti-platelet medications, or have a bleeding disorder, consult your healthcare provider before taking this product.

References

If you have any questions, please contact us at info@lifeextensionvitamins.com or 1-888-771-3905.
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Optimized Resveratrol - Life Extension - Non-GMO - 60 vegetarian capsules - 4-Pak
Retail Price: $166.00
Your Price: $124.00
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The statements made here have not been evaluated by the FDA. The foregoing statements are based upon sound and reliable studies, and are meant for informational purposes. Consult with your medical practitioner to determine the underlying cause of your symptoms. Please always check your purchase for possible allergins and correct dosage on the bottle before use.

While we work to ensure that product information is correct, on occasion manufacturers may alter their ingredient lists. Actual product packaging and materials may contain more and/or different information than that shown on our Web site. We recommend that you do not solely rely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. For additional information about a product, please contact the manufacturer. Content on this site is for reference purposes and is not intended to substitute for advice given by a physician, pharmacist, or other licensed health-care professional. You should not use this information as self-diagnosis or for treating a health problem or disease. Contact your health-care provider immediately if you suspect that you have a medical problem. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease or health condition. Life Extension Institute assumes no liability for inaccuracies or misstatements about products.