Life Extension Foundation
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One capsule contains 300 mg St John's Wort leaf and flower powder extract standardized to supply 0.3% (0.9 mg) hypericin.
Although biochemistry is a big factor, weíre also affected by what happens to us in our lives. Weíre all hit by unpleasant events that may cause brain levels of norepinephrine and dopamine to fall temporarily. People with naturally large reserves usually get through the troubling times with minimal difficulties, but those with initially low chemical levels are more likely to be affected.
St. Johnís Wort (Hypericum perforatum extract) is a weak inhibitor of monoamine oxidase (MAO),64 which destroys monoamine neurotransmitters including dopamine in the brain and leads to low spirits. St. Johnís Wort has also been shown to inhibit re-uptake of several neurotransmitters, such as serotonin, dopamine, noradrenaline, and GABA in the brain, and to reduce expression of interleukin-6.65-67 Each of these actions can contribute to alleviating low mood status by slowing the recycling of neurotransmitters needed for maintaining emotional balance. Flavonoids, hypericin and pseudo-hypericin, are the constituents thought to be associated with the benefits of St. Johnís Wort. In particular, hypericin appears to be the active ingredient.68-70Supplement FactsServing Size:
1 vegetarian capsuleServings Per Container:
60Amount per Serving - % DV
- St. John's Wort (Hypericum perforatum) Extract (whole herb) [std. to 0.3% (0.9 mg) hypericin] - 300mg
rice flour, vegetable cellulose (capsule), vegetable stearate.
Contains rice.Dosage and Use:
Take one capsule once or twice daily on an empty stomach, or as recommended by a healthcare practitioner.Caution:
Because St. Johnís Wort may have numerous drug interactions (most commonly, MAOIs and SSRIs) consult your healthcare provider before taking this product if you are taking prescription medications. Avoid prolonged exposure to UV radiation (e.g. sunlight, tanning) when using this product.
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