Melatonin's multi-modal effects
Melatonin may help prevent a number of age-related degenerative diseases. What follows are titles from just a few of the many published articles indicating the importance of maintaining youthful levels of melatonin.
A significant correlation between melatonin deficiency and endometrial cancer. Gynecol Obstet Invest 1998; 45(1):62-5.
Melatonin and regulation of the cardiovascular system. Therapie 1998 Sep-Oct;53(5):459-65.
Effect of melatonin on sleep quality of COPD intensive care patients: a pilot study. Chronobiol Int 2000 Jan;17(1):71-6.
Pharmacology and physiology of melatonin in the reduction of oxidative stress in vivo. Biol Signals Recept 2000 May-Aug; 9(3-4):160-71.
Is carbonyl detoxification an important anti-aging process during sleep? Med Hypotheses 2000 Apr;54(4):519-22.
Differential growth inhibitory effect of melatonin on two endometrial cancer cell lines. J Pineal Res 2000 28(4):227-33.
Melatonin as biological response modifier in cancer patients Anticancer Res 1998 Mar-Apr;18(2B):1329-32.
Melatonin deficiency: Its role in oncogenesis and age-related pathology. Journal of Orthomolecular Medicine (Canada) 1990, 5/1 (22-24).
Cataractogenesis and lipid peroxidation in newborn rats treated with buthionine sulfoximine: preventive actions of melatonin. J Pineal Res 1997 Apr;22(3):117-23.
Melatonin improves sleep quality of patients with chronic schizophrenia. J Clin Psychiatry 2000 May;61(5):373-7.
Effect of melatonin on proliferative activity and apoptosis in colon mucosa and colon tumors induced by 1,2-dimethylhydrazine in rats. Exp Toxicol Pathol 2000;52(1):71-6.
Influence of melatonin on proliferation and antioxidant system in Ehrlich ascites carcinoma cells. Cancer Lett 2000; 151(2):119-25.